Jenny McCarthy is the newest filly to join Oprah Winfrey's growing stable of talent. The one-time Playboy model has signed a multi-year deal with Harpo Productions. McCarthy has already transformed herself from blond bombshell to actress, author and advocate. Now, with backing from daytime's most successful diva, McCarthy is set to host her own talkfest.

With Winfrey set to launch her own cable net next year (a rebranded Discovery Health Channel), she needs new content. And McCarthy can deliver a fresh approach to the talk format. She is outspoken and does not shy away from expressing her opinion on controversial subjects such as the relationship between autism and vaccination. That Jenny McCarthy is dating Jim Carrey just adds to her marquee value.